Research in progress

Last updated: 6 May 2008 - Next update due: 13 May 2008

Projects are listed in order of intended publication date, soonest first. Followed by completed projects that do not require publication.

• Docetaxel for the adjuvant treatment of early breast cancer. HTA Ref: 05/53/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Early 2008.
  
• Are topical or oral Ibuprofen equally effective for the treatment of chronic knee pain in older people (Topical or Oral Ibuprofen TOIB). HTA Ref: 01/09/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: May 2008.
  
• Inhaled corticosteroids and long acting beta2 agonists for the treatment of chronic asthma in adults and children aged 12 years and over. HTA Ref: 04/30/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: May 2008.
  
• Inhaled corticosteroids and long acting beta2 agonists for the treatment of chronic asthma in children under the age of 12 years. HTA Ref: 04/30/02.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: May 2008.
  
• A review and critical analysis of studies assessing the nature and quality of therapist/patient interactions in treatment of patients with mental health problems. HTA Ref: 06/90/05.
  Research Type: Methodology.
  Estimated publication date: May 2008.
  
• A prospective randomised comparison of minor surgery in primary and secondary care. HTA Ref: 95/25/03.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: May 2008.
  
• STOOL - Stepped Treatment of Older adults On Laxatives. HTA Ref: 98/32/99.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: May 2008.
  
• What is the clinical and cost effectiveness of screening programmes for amblyopia and squint in children up to the ages of 4-5 years?. HTA Ref: 04/32/05.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: May 2008.
  
• The use of irinotecan, oxaliplatin and raltitrexed for the treatment of advanced colorectal cancer: systematic review and economic evaluation (review of NICE Guidance No. 33). HTA Ref: 04/12/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: May 2008.
  
• Ranibizumab and pegaptanib for the treatment of age-related macular degeneration. HTA Ref: 04/24/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: May 2008.
  
• Randomised trial of fluoxetine and cognitive-behavioural therapy versus fluoxetine alone in adolescents with persistent major depression. HTA Ref: 97/29/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: May 2008.
  
• Febuxostat for the management of hyperuricaemia in patients with gout. HTA Ref: 07/69/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  Estimated publication date: May 2008.
  
• Structural brain imaging in first episode psychosis. HTA Ref: 06/58/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: June 2008.
  
• Clinical and cost effectiveness of rimonabant within its licensed indications as an adjunct to diet and exercise for the treatment of obese and overweight patients. HTA Ref: 07/14/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Mid 2008.
  
• Venous thromboembolism - dabigatran. HTA Ref: 07/90/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  Estimated publication date: July 2008.
  
• Absorbent products for urinary/faecal incontinence: A comparative evaluation of key product categories. HTA Ref: 01/11/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: July 2008.
  
• Ezetimibe for the treatment of hypercholesterolaemia. HTA Ref: 05/22/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: July 2008.
  
• Systematic review of the clinical effectiveness and cost-effectiveness and economic modelling of minimal incision total hip replacement approaches in the management of arthritic disease of the hip. HTA Ref: 06/46/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: July 2008.
  
• Is a screening programme for early age-related macular degeneration likely to be cost-effective? What are the major areas of uncertainty?. HTA Ref: 03/06/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: July 2008.
  
• Gemcitabine for advanced/metastatic breast cancer. HTA Ref: 06/16/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Mid 2008.
  
• Rituximab for the first line treatment of low grade follicular non-Hodgkin's lymphoma. HTA Ref: 05/55/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Mid 2008.
  
• Cetuximab for metastatic first line colorectal cancer. HTA Ref: 07/91/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  Estimated publication date: July 2008.
  
• A systematic review of repetitive task training with modelling of resource use, costs and effectiveness. HTA Ref: 05/17/04.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: July 2008.
  
• A randomised controlled trial to estimate the clinical and cost-effectiveness of four different methods of mechanical support in severe ankle sprains (CAST). HTA Ref: 01/14/10.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: August 2008.
  
• Infliximab for the treatment of acute exacerbations of ulcerative colitis. HTA Ref: 08/37/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  Estimated publication date: August 2008.
  
• Bortezomib for multiple myeloma. HTA Ref: 05/56/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Mid 2008.
  
• Adalimumab for the treatment of psoriasis. HTA Ref: 07/71/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Mid 2008.
  
• Natalizumab for multiple sclerosis. HTA Ref: 06/65/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Mid 2008.
  
• Alteplase for acute ischaemic stroke. HTA Ref: 06/51/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Mid 2008.
  
• Adalimumab for the treatment of moderate to severe psoriatic arthritis. HTA Ref: 06/54/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Mid 2008.
  
• Accuracy of screening procedures for non-accidental injury in children: systematic review and modelling of clinical effectiveness. HTA Ref: 03/37/06.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: August 2008.
  
• Rituximab for the treatment of refractory rheumatoid arthritis. HTA Ref: 06/53/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Mid 2008.
  
• Fludarabine for lymphocytic leukaemia. HTA Ref: 06/17/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Mid 2008.
  
• Erlotinib for the treatment of relapsed non-small cell lung cancer. HTA Ref: 06/23/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Mid 2008.
  
• Pemetrexed for the treatment of relapsed non-small cell lung cancer. HTA Ref: 06/24/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Mid 2008.
  
• Curative catheter ablation in atrial fibrillation and typical atrial flutter. HTA Ref: 06/13/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: September 2008.
  
• Intravenous magnesium compared with sotalol for prevention of atrial fibrillation after coronary artery bypass surgery. HTA Ref: 07/18/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: September 2008.
  
• Use of classical and novel biomarkers as prognostic risk factors for prostate cancer. HTA Ref: 06/27/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: September 2008.
  
• Screening to prevent pre-term birth - systematic reviews of accuracy and effectiveness literature with economic modelling. HTA Ref: 05/03/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: September 2008.
  
• Lapatinib for HER2 over-expressing breast cancer. HTA Ref: 07/10/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Late 2008.
  
• Improving the evaluation of therapeutic interventions in multiple sclerosis: the role of new pyschometric methods - new analyses of the original study results. HTA Ref: 95/01/05.
  Research Type: Methodology.
  Estimated publication date: September 2008.
  
• Varenicline for smoking cessation. HTA Ref: 06/50/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Late 2008.
  
• Immunoprophylaxis against RSV with palivizumab in children - A systematic review and economic evaluation. HTA Ref: 06/29/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: October 2008.
  
• Systematic review of the clinical effectiveness and cost-effectiveness of oesophageal Doppler monitoring in critically ill and high risk surgical patients. HTA Ref: 07/20/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: October 2008.
  
• Cetuximab in its licensed indications for refractory head and neck cancer. HTA Ref: 06/25/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Late 2008.
  
• Omalizumab for severe persistent allergic asthma. HTA Ref: 06/64/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Late 2008.
  
• The place of minimal access surgery amongst people with gastro-oesophageal reflux disease (GORD) - a UK collaborative study. HTA Ref: 97/10/03.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: October 2008.
  
• Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement (BPE). HTA Ref: 04/38/03.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: October 2008.
  
• Continuous subcutaneous insulin infusion for the treatment of diabetes (update of Guidance No 57). HTA Ref: 06/61/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: October 2008.
  
• Thrombophilia testing. HTA Ref: 06/66/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: October 2008.
  
• Systematic review of the clinical and cost-effectiveness, and economic evaluation, of photodynamic diagnosis and urine biomarker tests in the detection and follow-up of bladder cancer. HTA Ref: 07/02/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: Late 2008.
  
• Psychological interventions for postnatal depression - randomised controlled trial and economic evaluation (PONDER). HTA Ref: 99/33/51.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: November 2008.
  
• Cannabinoids (cannabis derivatives) for treatment of the symptoms of multiple sclerosis. HTA Ref: 02/23/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: Late 2008.
  
• BELL'S trial: bell's palsy: early acyclovir or prednisolone in Scotland. HTA Ref: 02/09/04.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: December 2008.
  
• Abatacept for the treatment of refractory rheumatoid arthritis. HTA Ref: 06/52/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Late 2008.
  
• Pregnancy - routine anti-D prophylaxis for rhesus negative women (review) (update of NICE Guidance 41 with inclusion of a new drug - rhophylac). HTA Ref: 07/05/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: January 2009.
  
• Infliximab for psoriasis. HTA Ref: 06/67/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Early 2009.
  
• Clinical and cost effectiveness of epoprostenol, iloprost, bosentan, sitaxentan, and sildenafil for the treatment of pulmonary arterial hypertension in adults: a systematic review and economic evaluation. HTA Ref: 05/24/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: January 2009.
  
• Diagnostic strategies using DNA testing for hereditary haemochromatosis in at-risk populations. HTA Ref: 05/07/04.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: January 2009.
  
• Paclitaxel for the adjuvant treatment of early breast cancer. HTA Ref: 05/54/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Early 2009.
  
• The effectiveness and cost-effectiveness of cochlear implants for severe to profound deafness in children and adults. HTA Ref: 06/59/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: January 2009.
  
• Aspirin in the primary prevention of cardiovascular disease. HTA Ref: 06/10/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: Early 2009.
  
• Non-pharmacological interventions to reduce the risk of diabetes in people with impaired glucose regulation: systematic review and economic evaluation. HTA Ref: 06/11/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: Early 2009.
  
• The clinical and cost-effectiveness of computed tomography as an alternative to angiography in investigation of coronary artery disease. HTA Ref: 06/15/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: Early 2009.
  
• A systematic review of the effectiveness of biofeedback for the treatment of essential hypertension in adults. HTA Ref: 07/04/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: Early 2009.
  
• Continuous positive airways pressure (CPAP) for the treatment of obstructive sleep apnoea/hypopnoea syndrome (OSAHS). HTA Ref: 06/57/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: Early 2009.
  
• Probabilistic sensitivity analysis: an audit of current practice and a review of its use and value in decision making. HTA Ref: 07/56/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: Early 2009.
  
• Adverse effects in economic models: Are they incorporated adequately and appropriately?. HTA Ref: 07/57/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: Early 2009.
  
• Spinal cord stimulation for chronic pain of neuropathic or ischaemic origin. HTA Ref: 07/08/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: Early 2009.
  
• Endovascular stents for abdominal aortic aneurysms: a systematic review and economic model. HTA Ref: 07/09/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: Early 2009.
  
• Oseltamivir, amantadine and zanamivir for the prophylaxis of influenza (including a review of existing guidance no. 67).. HTA Ref: 07/35/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: Early 2009.
  
• Early high dose lipid-lowering therapy to prevent cardiac events. HTA Ref: 07/03/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: Early 2009.
  
• Bevacizumab, sorafenib tosylate and sunitinib for renal cell carcinoma. HTA Ref: 07/72/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: Early 2009.
  
• Vitamin K to prevent fractures in older women. HTA Ref: 07/16/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: Early 2009.
  
• Enhanced external counterpulsation (EECP) for stable angina or heart failure. HTA Ref: 07/62/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: Early 2009.
  
• Adefovir dipivoxil and pegylated interferon alfa for the treatment of chronic hepatitis B: an updated systematic review and economic evaluation. HTA Ref: 07/15/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: Early 2009.
  
• Deferasirox for the treatment of iron overload associated with regular blood transfusions (transfusional hemosiderosis) in patients suffering with chronic anaemia. HTA Ref: 06/12/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: January 2009.
  
• Time to full publication of studies of novel chemotherapy drugs for breast cancer, and the potential for publication bias. HTA Ref: 07/55/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: January 2009.
  
• Systematic review of the literature on respite care for the frail elderly. HTA Ref: 04/07/06.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: January 2009.
  
• Infliximab for the sub-acute manifestations of ulcerative colitis. HTA Ref: 07/12/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Early 2009.
  
• The effect of withdrawal of clopidogrel in patients with ischaemic heart disease. HTA Ref: 07/19/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: February 2009.
  
• Clinical and cost effectiveness of the tumour necrosis factor alpha (TNF a) inhibitors within their licensed indications for Crohn's disease (part update of Guidance No 40). HTA Ref: 06/60/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: February 2009.
  
• Non-occupational post-exposure prophylaxis for HIV. HTA Ref: 07/40/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: Early 2009.
  
• The clinical and cost effectiveness of testing for cytochrome P450 polymorphisms in patients treated with antipsychotics. HTA Ref: 06/28/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: Early 2009.
  
• Surgical procedures and non-surgical devices for the management of non-apnoeic snoring: a systematic review of clinical effects and associated treatment costs. HTA Ref: 07/17/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: March 2009.
  
• The effectiveness and cost-effectiveness of machine perfusion systems and cold static storage of donated kidneys. HTA Ref: 07/07/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: Early 2009.
  
• Conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR). HTA Ref: 99/01/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2009.
  
• A randomised 2x2 trial of community versus hospital rehabilitation, followed by telephone or conventional follow up; impact on quality of life, exercise capacity and use of health care resources. HTA Ref: 01/15/10.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2009.
  
• A double-blind randomised placebo-controlled trial of topical nasal steroids in 4-11 year old children with persistent bilateral Otitis Media with Effusion (OME) in primary care. HTA Ref: 01/72/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2009.
  
• Randomised controlled trial to determine the cost-effectiveness of fluoxetine for mild to moderate depression with somatic symptoms in primary care - THREshold for AntiDepressant treatment (THREAD). HTA Ref: 01/70/05.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2009.
  
• Zanamivir, oseltamivir and amantadine for the treatment of influenza (an update review of existing guidance No. 58). HTA Ref: 07/74/01.
  Research Type: NICE Technology Assessment Report (TAR).
  Estimated publication date: Early 2009.
  
• Randomised controlled trial of the use of three dressing regimens in the management of chronic ulcers of the foot in diabetes. HTA Ref: 01/74/03.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: March 2009.
  
• How far does screening women for partner violence in different health care settings meet the UK National Screening Committee criteria for a screening programme in terms of condition, screening method and intervention?. HTA Ref: 05/09/07.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: March 2009.
  
• Randomised controlled trial of continuous positive airways pressure and non-invasive positive pressure ventilation in the management of patients presenting with acute cardiogenic pulmonary oedema (3CPO). HTA Ref: 01/43/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2009.
  
• VenUS II: larval therapy venous ulcer study. HTA Ref: 01/41/04.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2009.
  
• Antenatal screening for haemoglobinopathies in primary care: a cluster randomised trial to inform a simulation model (SHIFT). HTA Ref: 03/02/03.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2009.
  
• Trastuzumab as adjuvant therapy for early stage breast cancer. HTA Ref: 05/51/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Early 2009.
  
• Assessment of the use of surrogate outcomes in model-based cost effectiveness analyses within UK health technology assessment reports. HTA Ref: 07/53/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: April 2009.
  
• The harmful health effects of recreational ecstasy: a systematic review of observational evidence. HTA Ref: 07/64/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: April 2009.
  
• A pragmatic single-blind RCT and health economic evaluation of leukotriene receptor antagonists in primary care at steps two and three of the national asthma guidelines (ELEVATE). HTA Ref: 98/34/05.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: April 2009.
  
• Controlling hypertension and hypotension immediately post-stroke (CHHIPS) trial. HTA Ref: 01/73/03.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: April 2009.
  
• What are the pros and cons of screening high risk populations for anal cancer?. HTA Ref: 05/11/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: April 2009.
  
• A randomised controlled trial to determine the effect of blood glucose self-monitoring in people with type 2 diabetes (DiGEM). HTA Ref: 01/38/05.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: May 2009.
  
• Rehabilitation of older patients: day hospital compared to rehabilitation at home. HTA Ref: 97/26/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: May 2009.
  
• Systematic review and individual patient data meta-analysis of diagnosis of heart failure, with modelling of the implications of different diagnostic strategies in primary care. HTA Ref: 05/06/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: May 2009.
  
• Antidepressant drug therapy vs a community-based psychosocial intervention for the treatment of moderate postnatal depression: a pragmatic randomised controlled trial (RESPOND). HTA Ref: 02/07/04.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2009.
  
• Development and randomised controlled trial of dipsticks and diagnostic algorithms for the management of UTI. HTA Ref: 97/14/06.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: May 2009.
  
• Accuracy and cost effectiveness of rapid diagnosis of Group-B streptococcus during labour. HTA Ref: 02/38/04.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: May 2009.
  
• A randomised control trial to compare minimally invasive glucose monitoring devices to conventional monitoring in the management of insulin treated diabetes mellitus (MITRE). HTA Ref: 01/13/03.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: May 2009.
  
• Glucosamine and chondroitin for osteoarthritis of the knee. HTA Ref: 07/61/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: Mid 2009.
  
• The role of magnetic resonance imaging in the identification of suspected acoustic neuroma: systematic review of clinical and cost effectiveness, and natural history. HTA Ref: 05/08/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: May 2009.
  
• Ibuprofen and paracetamol in combination and separately for fever in pre-school children presenting to primary care: a randomised controlled trial (PITCH). HTA Ref: 03/09/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: June 2009.
  
• Randomised controlled trial and economic modelling to evaluate the place of anti-microbial agents in the management of venous leg ulcers (VULCAN). HTA Ref: 02/10/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2009.
  
• A randomised preference trial of medical versus surgical termination of pregnancies less than 14 weeks' gestation (TOPS). HTA Ref: 03/11/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2009.
  
• An update of two Cochrane reviews 'Peer reviewing for improving the quality of grant applications' and 'Editorial peer review for improving the quality of reports of biomedical studies'. HTA Ref: 06/90/17.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• Comparison of the results of RCT's with other study designs. HTA Ref: 06/90/22.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• A review of, and primary research into, approaches to the elicitation of individuals' (Bayesian) prior probabilities. HTA Ref: 06/91/01.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• Comparative study of different methods to assess quality of care/safety. HTA Ref: 06/91/02.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• Enabling the Cochrane methodology register to serve the NHS R&D methodology group more effectively. HTA Ref: 06/91/03.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• The relative societal value of health gains for different beneficiaries. HTA Ref: 06/91/04.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• Mode Of Data Elicitation, Acquisition and Response To Surveys (MODE ARTS). HTA Ref: 06/91/07.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• Satisfaction in Life for Children With Own Report Measures (SILCWORM). HTA Ref: 06/91/08.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• Cessation of Attention deficit hyperactivity Disorder Drugs in Young (CADDY). HTA Ref: 04/36/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2009.
  
• The clinical and cost-effectiveness of different treatment pathways for neuropathic pain (NP). HTA Ref: 05/30/03.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: Mid 2009.
  
• Addressing ethnic diversity in health care outcome measurement. HTA Ref: 06/90/06.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• Systematic appraisal and synthesis of qualitative research: evaluating meta ethnography. HTA Ref: 06/90/12.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• Critical review of outcome measures for use in forensic mental health studies. HTA Ref: 06/91/11.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• Developing an instrument to measure social inclusion - a literature review and consensus exercise (phase 1). HTA Ref: 06/91/12.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• Risk factors for surgical wound infection. HTA Ref: 06/90/19.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• Missing data in randomised clinical trials. HTA Ref: 06/90/24.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• Review of the validity and reliability of measures of human resource management. HTA Ref: 06/91/06.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• Development of a "social inclusion index" to capture subjective and objective domains (phase 1). HTA Ref: 06/91/13.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• Cross trimester repeated measures testing for Down's syndrome screening. HTA Ref: 06/08/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2009.
  
• A comparison and discussion of the methods, findings, adaptability and decisions resulting from two reviews of vision screening in children undertaken in the UK and Germany. HTA Ref: 05/52/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: Mid 2009.
  
• What is the value to society of a QALY?. HTA Ref: 06/91/05.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• Breastfeeding promotion in special care and neonatal intensive care units (SCBU/NICU ); an evidence synthesis. HTA Ref: 06/34/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: Mid 2009.
  
• Rituximab for the treatment of recurrent or refractory stage III or IV follicular non-Hodgkin's lymphoma (Review of TA 37). HTA Ref: 06/87/01.
  Research Type: NICE Evidence Review Group Report (ERG).
  (ERG report received)
  Estimated publication date in Supplement to the HTA journal series: Mid 2009.
  
• North of England study of tonsillectomy and adeno-tonsillectomy in children (NESSTAC). HTA Ref: 99/20/03.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2009.
  
• Avoiding and identifying errors in health technology assessment models. HTA Ref: 07/54/01.
  Research Type: HTA Technology Assessment Report.
  Estimated publication date: Mid 2009.
  
• A randomised trial of human papilloma virus testing in primary cervical screening (ARTISTIC). HTA Ref: 98/04/64.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: July 2009.
  
• Assessing and comparing mean costs of care in health economic evaluations based on clinical trials. HTA Ref: 06/91/09.
  Research Type: Methodology.
  Estimated publication date: Mid 2009.
  
• Development of a decision support tool to facilitate primary care management of patients with abnormal liver function tests without clinically apparent liver disease (ALFIE). HTA Ref: 03/38/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: August 2009.
  
• Multi-centre randomised controlled trial examining the cost-effectiveness of contrast-enhanced high field magnetic resonance imaging in women scheduled for wide local excision (COMICE). HTA Ref: 99/27/05.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2009.
  
• A multi-centred randomised controlled trial of a primary-care based cognitive behavioural programme for low back pain (UK-Best). HTA Ref: 01/75/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2009.
  
• Neuroleptics in adults with aggressive challenging behaviour and intellectual disability (NACHBID). HTA Ref: 01/07/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: September 2009.
  
• A randomised controlled trial of cognitive behaviour therapy and motivational interviewing for people with Type 1 diabetes mellitus and suboptimal glycaemic control (ADaPT). HTA Ref: 01/17/05.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: September 2009.
  
• RCT to evaluate impact of diagnostic testing for influenza, respiratory syncytial virus and streptococcus pneumoniae infection on the management of acute admissions in the elderly. HTA Ref: 03/39/18.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2009.
  
• Managing Injuries of the Neck Trial (MINT). HTA Ref: 02/35/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2009.
  
• What is the clinical effect and cost effectiveness of treating upper limb spasticity due to stroke with botulinum toxin?. HTA Ref: 02/41/06.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2009.
  
• The clinical validity, utility and cost effectiveness of methods for the identification of postnatal depression (PND) in primary care: an integrated evidence synthesis and value of information analysis. HTA Ref: 05/39/06.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: October 2009.
  
• The effectiveness and cost effectiveness of biomarkers for the prioritisation of patients awaiting coronary revascularisation: a systematic review and decision model. HTA Ref: 05/40/04.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: Late 2009.
  
• Molecular diagnosis of central venous catheter (CVC) associated infections. HTA Ref: 03/39/13.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2009.
  
• HTA study of antidepressants for depression in dementia - a definitive multicentre pragmatic randomised controlled trial of clinical and cost effectiveness (HTA-SADD). HTA Ref: 04/11/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2009.
  
• Dissemination bias in medical and health related research - an updated synthesis of empirical evidence and a critical assessment of available methods. HTA Ref: 06/92/02.
  Research Type: Methodology.
  Estimated publication date: Late 2009.
  
• A randomised controlled multi-centre treatment trial of adolescent anorexia nervosa, including assessment of cost effectiveness and patient acceptability. HTA Ref: 97/42/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2009.
  
• Communication of carrier status information following newborn screening: descriptive study of current practice, methods and experience. HTA Ref: 04/10/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2009.
  
• European Network for Health Technology Assessment - EuNetHTA. HTA Ref: 05/52/01.
  Research Type: Other types of research.
  Estimated publication date: Late 2009.
  
• Colour vision testing in diabetic retinopathy: a systematic review and cost-effectiveness analysis. HTA Ref: 07/28/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: Late 2009.
  
• CT colonography, colonoscopy or barium enema for diagnosis of colorectal cancer in older symptomatic patients (SIGGAR1). HTA Ref: 02/02/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2009.
  
• Systematic review and economic modelling of the effectiveness and efficiency of non-surgical treatments for women with stress urinary incontinence (SUI). HTA Ref: 06/41/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: Early 2010.
  
• Frequency of follow-up for patients with intermediate grade colorectal adenomas. HTA Ref: 04/33/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2010.
  
• Development and evaluation of a psychosocial intervention for children and teenagers experiencing diabetes (the DEPICTED Study). HTA Ref: 03/46/09.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2010.
  
• Cryotherapy versus salicylic acid for the treatment of verrucae: A randomised controlled trial. HTA Ref: 05/513/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2010.
  
• Towards single embryo transfer. Modelling clinical outcomes of potential treatment choices using multiple data sources: predictive models and patient perspectives.. HTA Ref: 05/43/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2010.
  
• Quantification of bias in randomised controlled trials and non-randomised studies: implications for systematic reviews and evidence synthesis (BRANDO study). HTA Ref: 06/91/10.
  Research Type: Methodology.
  Estimated publication date: Early 2010.
  
• A single blind randomised controlled trial to determine the effectiveness and cost utility of manual chest physiotherapy techniques in the management of exacerbations of chronic obstructive pulmonary disease (MATREX). HTA Ref: 03/13/06.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2010.
  
• Verteporfin photodynamic therapy cohort study for the UK. HTA Ref: 03/36/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2010.
  
• Early referral strategies for patients with markers of renal disease. HTA Ref: 06/75/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: Early 2010.
  
• The safety and effectiveness of different methods of ear wax removal: a systematic review and economic evaluation.. HTA Ref: 06/77/04.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: Mid 2010.
  
• The RATPAC Trial: Randomised Assessment of Treatment using Panel Assay of Cardiac markers. HTA Ref: 06/302/19.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2010.
  
• Effectiveness and cost effectiveness of hysterectomy, microwave endometrial ablation and thermal balloon ablation for the treatment of menorrhagia. HTA Ref: 05/45/02.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: Mid 2010.
  
• Assessment of surgical skills of trainees and consultants in the operating theatre. HTA Ref: 06/92/05.
  Research Type: Methodology.
  Estimated publication date: Mid 2010.
  
• Evaluate the clinical and cost effectiveness of group cognitive behavioural therapy for post-natal depression. HTA Ref: 06/83/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: Mid 2010.
  
• An evidence synthesis of qualitative and quantitative research on the component intervention techniques, effectiveness, cost-effectiveness, equity and acceptability of different versions of health-related lifestyle adviser role in improving health. HTA Ref: 07/26/03.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: Mid 2010.
  
• School-linked Sexual Health Services for Young People (SSHYP): current models, costs and effectiveness.. HTA Ref: 06/69/03.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: Mid 2010.
  
• Chemoprevention of colorectal cancer: systematic review and economic model. HTA Ref: 06/70/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: Mid 2010.
  
• The use of MElatonin in children with Neuro-Developmental disorders and impaired sleep; a randomised, double-blind, placebo-controlled, parallel Study (MENDS). HTA Ref: 05/14/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2010.
  
• Relapse prevention in NHS stop smoking services: Current practice, potential effectiveness and cost effectiveness. HTA Ref: 06/32/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: Mid 2010.
  
• Folate Augmentation of Treatment - Evaluation for Depression: randomised controlled trial (FolATED). HTA Ref: 04/35/08.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2010.
  
• Development of a social inclusion index to capture subjective and objective life domains (phase 2). HTA Ref: 06/91/16.
  Research Type: Methodology.
  Estimated publication date: Late 2010.
  
• Safety and harms of antidepressant drugs for older people: an analysis using a large primary care database. HTA Ref: 06/42/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2010.
  
• VenUS III - Venous Ulcer Studies III: ultrasound for venous leg ulcers. HTA Ref: 02/37/03.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2010.
  
• A comparison of automated technology and manual cervical screening (MAVARIC). HTA Ref: 03/04/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2010.
  
• Pre-operative testing: evidence synthesis, cost effectiveness and value of information analysis.. HTA Ref: 06/84/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: Late 2010.
  
• Randomised controlled trial of ion-exchange water softeners for the treatment of atopic eczema in children (SWET). HTA Ref: 05/16/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2010.
  
• Evaluation of patient reporting to the Yellow Card System. HTA Ref: 06/92/03.
  Research Type: Methodology.
  Estimated publication date: Late 2010.
  
• Management strategies for sciatica. HTA Ref: 06/79/01.
  Research Type: Secondary Research (e.g. systematic review).
  Estimated publication date: Late 2010.
  
• Cancer of the oesophagus or gastricus: new assessment of the technology of endosonography (COGNATE). HTA Ref: 01/01/03.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2010.
  
• Types of urethral catheter for reducing symptomatic urinary tract infections in hospitalised adults requiring short-term catheterisation: multicentre randomised controlled trial of antibiotic and antiseptic impregnated urethral catheters. HTA Ref: 05/46/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2011.
  
• The measurement of patients' expectations for health care. HTA Ref: 07/58/01.
  Research Type: Methodology.
  Estimated publication date: Early 2011.
  
• Assessing the effectiveness of Communication Therapy in the North West (the ACT NoW study). HTA Ref: 02/11/04.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2011.
  
• Conservative treatment for urinary incontinence in men after prostate surgery (MAPS). HTA Ref: 03/14/03.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2011.
  
• Processes in recruitment to randomised controlled trials (RCTs) of medicines for children (RECRUIT). HTA Ref: 05/516/08.
  Research Type: Methodology.
  Estimated publication date: Early 2011.
  
• The PRIME breast cancer trial (postoperative radiotherapy in minimum-risk elderly). HTA Ref: 96/03/99.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2011.
  
• Pulse oximetry as a screening test for congenital heart disease in newborn babies. HTA Ref: 06/06/03.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2011.
  
• Improving the value of screening for diabetic macular oedema using surrogate photographic markers. HTA Ref: 06/402/49.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2011.
  
• Effectiveness and cost-effectiveness of arthroscopic lavage in the treatment of osteoarthritis of the knee (the KORAL study). HTA Ref: 03/48/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2011.
  
• Birmingham And Lambeth Liver Evaluation Testing Strategies - BALLETS. HTA Ref: 03/38/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2011.
  
• The EndoVascular Aneurysm Repair (EVAR) trials 1 and 2: follow-up. HTA Ref: 95/02/99.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2011.
  
• Randomised controlled trial of tumour-necrosis-factor inhibitors against combination intensive therapy with conventional disease modifying anti-rheumatic drugs in established rheumatoid arthritis: the TACIT trial. HTA Ref: 06/303/84.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2011.
  
• A longitudinal cohort study of people with lysosomal storage disorders. HTA Ref: 05/04/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2011.
  
• Bereavement and randomised controlled trials: a methodological study of policy and practice in neonatal and paediatric intensive care trials. HTA Ref: 05/516/06.
  Research Type: Methodology.
  Estimated publication date: Late 2011.
  
• Comparison of culture tools with holistic evaluation of an organisation's culture. HTA Ref: 06/92/06.
  Research Type: Methodology.
  Estimated publication date: Late 2011.
  
• The 3Mg Trial: Randomised controlled trial of intravenous or nebulised magnesium sulphate or standard therapy for acute severe asthma. HTA Ref: 06/01/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2011.
  
• A randomised controlled trial of different knee prostheses. HTA Ref: 95/10/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2011.
  
• PRImary care Streptococcal Management study (PRISM). HTA Ref: 05/10/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2011.
  
• CRASH2 Trial, a large randomised placebo controlled trial among trauma patients with significant haemorrhage of the effects of an antifibrinolytic treatment on death and transfusion requirement. HTA Ref: 06/303/20.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2011.
  
• The effectiveness and cost-effectiveness of opportunistic screening and stepped care interventions for older hazardous alcohol users in primary care (AESOPS). HTA Ref: 06/304/142.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2011.
  
• Evaluation of mammographic surveillance services in women under 50 with a family history of breast cancer (FH01). HTA Ref: 01/18/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2011.
  
• A pragmatic randomised controlled trial to evaluate exercise prescription as a treatment for depression (TREAD). HTA Ref: 03/45/07.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2011.
  
• Interactive group art therapy as an adjunctive treatment for people with schizophrenia (MATISSE). HTA Ref: 04/39/04.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2012.
  
• SLEEPS: Safety profiLe, Efficacy and Equivalence in Paediatric intensive care Sedation: A Comparison of Clonidine and Midazolam. HTA Ref: 05/515/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2012.
  
• Management of Asthma in School-aged Children On Therapy - MASCOT. HTA Ref: 05/503/04.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2012.
  
• MAGnesium NEbuliser Trial In Children (MAGNETIC). HTA Ref: 05/503/10.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2012.
  
• Reminiscence groups for people with dementia and their family care-givers: pragmatic 8-centre trial of joint reminiscence and maintenance versus usual treatment. HTA Ref: 06/304/229.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2012.
  
• A randomised controlled trial to assess the cost-effectiveness of intensive versus no scheduled follow-up in patients who have undergone resection for colorectal cancer with curative intent (The FACS Trial). HTA Ref: 99/10/99.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2012.
  
• A randomised controlled trial (RCT) of alternative treatments to Inhibit VEGF in patients with Age-related choroidal Neovascularisation (IVAN). HTA Ref: 07/36/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2012.
  
• Infrastructure for guideline development. HTA Ref: 06/92/01.
  Research Type: Methodology.
  Estimated publication date: Mid 2012.
  
• Control of Hyperglycaemia in Paediatric intensive care trial (the CHIP trial). HTA Ref: 05/506/03.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2012.
  
• The place of minimal access surgery amongst people with gastro-oesophageal reflux disease - extended follow-up REFLUX-2. HTA Ref: 97/10/99.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2012.
  
• A large randomised assessment of the relative cost-effectiveness of different classes of drugs for Parkinson's disease (PD MED). HTA Ref: 98/03/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2012.
  
• Older People's Exercise intervention in Residential and nursing Accommodation (OPERA). HTA Ref: 06/02/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2012.
  
• Early administration to preterm infants of the probiotic bifidobacterium breve strain BBG to prevent infection and necrotising enterocolitis. HTA Ref: 05/501/04.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2012.
  
• Double-blind, randomised, placebo-controlled trial of nicotine replacement therapy (NRT) in pregnancy - SNAP. HTA Ref: 06/07/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2012.
  
• Cognitive behavioural therapy as an adjunct to pharmacotherapy for treatment resistant depression in primary care: a randomised controlled trial. HTA Ref: 06/404/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2013.
  
• A randomised controlled trial of high frequency oscillatory ventilation in patients with acute respiratory distress syndrome (OSCAR). HTA Ref: 06/04/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2013.
  
• Asymptomatic Carotid Surgery Trial-2 (ACST-2): an international randomised trial to compare carotid endarterectomy with carotid artery stenting to prevent stroke. HTA Ref: 06/301/233.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2013.
  
• The clinical and cost-effectiveness of surgical (arthroscopic or open) versus rest then exercise management for tears of the rotator cuff (UKUFF trial). HTA Ref: 05/47/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2013.
  
• Pragmatic multi-centre randomised trial of surgical versus non-surgical treatment for proximal fracture of the humerus in adults. HTA Ref: 06/404/53.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Late 2013.
  
• A randomised phase III trial of Docetaxel plus Prednisolone vs. Docetaxel with Prednisolone plus either Zoledronic acid, Strontium-89 or both agents combined (TRAPEZE). HTA Ref: 06/303/205.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2014.
  
• Effectiveness and Cost-effectiveness of Levonorgestrel containing Intrauterine system in Primary care against Standard trEatment - The ECLIPSE Trial. HTA Ref: 02/06/02.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2014.
  
• PERSEPHONE - Duration of Trastuzumab Study with Chemotherapy in Early Breast Cancer: Six versus twelve months. HTA Ref: 06/303/98.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2014.
  
• Positron Emission Tomography-Computerised Tomography scans (PET-CT) guided watch and wait policy versus planned neck dissection for the management of locally advanced (N2/N3) nodal metastases in patients with head and neck squamous cancer. HTA Ref: 06/302/129.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Mid 2014.
  
• The ProtecT trial - evaluating the effectiveness of treatments for clinically localised prostate cancer. HTA Ref: 96/20/99.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2015.
  
• A randomised controlled trial of a protease inhibitor monotherapy versus continuing combination antiretroviral therapy for HIV-1 infected patients previously established on a dual nucleoside and non-nucleoside combination regimen. HTA Ref: 06/403/90.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2015.
  
• Multi-centre randomised controlled trial of the cost-effectiveness of infra-inguinal percutaneous transluminal angioplasty (PTA) versus reconstructive surgery for severe limb ischaemia (BASIL). HTA Ref: 96/05/01.
  Research Type: Primary Research (e.g. trial).
  Estimated publication date: Early 2017.
  
• UK home parenteral nutrition register. HTA Ref: 93/38/05.
  Research Type: Secondary Research (e.g. systematic review). No publication required.
  
• Translation of Spanish report on routine pre-operative testing. HTA Ref: 93/55/01.
  Research Type: Secondary Research (e.g. systematic review). No publication required.
  
• Prostate trials office (PROTO): co-ordinating trials of new technologies in the treatment of BPH. HTA Ref: 94/04/05.
  Research Type: Methodology. No publication required.
  
• Development of the protocol for the proposed trial of beta interferon in multiple sclerosis. HTA Ref: 95/01/04.
  Research Type: Methodology. No publication required.
  
• Selective estrogen receptor modulators for osteoporosis. HTA Ref: 98/06/99.
  Research Type: Secondary Research (e.g. systematic review). No publication required.
  
• Endovascular aortic aneurysm repair (EVAR) trials. HTA Ref: 95/02/02.
  Research Type: Primary Research (e.g. trial). No publication required.
  
• A systematic evaluation of the clinical and cost effectiveness of 'atypical' anti-psychotics in the treatment of schizophrenia. HTA Ref: 96/18/99.
  Research Type: Secondary Research (e.g. systematic review). No publication required.
  
• Clinical and economic evaluation of hyaluronate membranes for prevention of complications of intra-abdominal adhesions. HTA Ref: 97/34/01.
  Research Type: Primary Research (e.g. trial). No publication required.
  
• Systematic review and economic modelling of the use of neuraminidase inhibitors for the prevention and treatment of influenza A and B. HTA Ref: 98/01/02.
  Research Type: Secondary Research (e.g. systematic review). No publication required.
  
• Inhaler systems (devices) for childhood asthma. HTA Ref: 99/19/01.
  Research Type: NICE Technology Assessment Report (TAR). No publication required.
  
• Methods for identifying and classifying surgical site infection after discharge from hospital. HTA Ref: 06/90/14.
  Research Type: Methodology. No publication required.
  
• Evaluation of the Citizen's Council of NICE. HTA Ref: 06/90/15.
  Research Type: Methodology. No publication required.
  
• The value of a QALY implied by the value of a 'statistical life' in the field of transport. HTA Ref: 06/90/18.
  Research Type: Methodology. No publication required.
  
• Testing treatments on animals: relevance to humans. HTA Ref: 06/90/21.
  Research Type: Methodology. No publication required.
  
• The clinical and cost-effectiveness of trastuzumab and vinorelbine for breast cancer.. HTA Ref: 00/15/01.
  Research Type: NICE Technology Assessment Report (TAR). No publication required.
  
• A randomised controlled trial to assess the cost-effectiveness of intensive versus no scheduled follow-up in patients who have undergone resection for colorectal cancer with curative intent. HTA Ref: 99/10/09.
  Research Type: Primary Research (e.g. trial). No publication required.
  
• Taxanes (breast cancer): update. HTA Ref: 99/17/02.
  Research Type: NICE Technology Assessment Report (TAR). No publication required.
  
• Taxanes (ovarian cancer): update. HTA Ref: 99/17/03.
  Research Type: NICE Technology Assessment Report (TAR). No publication required.
  
• Update briefing paper on Positron Emission Tomography (PET) for cancer management. HTA Ref: 04/13/01.
  Research Type: Other types of research. No publication required.
  
• Antenatal screening for group B streptococcus colonisation - protocol development. HTA Ref: 05/05/01.
  Research Type: Methodology. No publication required.
  
• Prevention of colonisation with pseudomonas aeruginosa for cystic fibrosis patients. HTA Ref: 06/21/01.
  Research Type: Primary Research (e.g. trial). No publication required.
  
• The validity of aggregation methods in cost-utility analysis: what is the descriptive validity of the convention that "a QALY is a QALY is a QALY". HTA Ref: 06/90/01.
  Research Type: Methodology. No publication required.
  
• What is the value to society of a QALY? A proposal to write a protocol. HTA Ref: 06/90/02.
  Research Type: Methodology. No publication required.
  
• What is the value to society of a QALY: an investigation among the public in England and Wales. HTA Ref: 06/90/03.
  Research Type: Methodology. No publication required.
  
• Developing the Cochrane methodology register. HTA Ref: 06/90/07.
  Research Type: Methodology. No publication required.
  
• Evaluation of NICE guidance. HTA Ref: 06/90/08.
  Research Type: Methodology. No publication required.
  
• Scoping study on the assessment of the star ratings. HTA Ref: 06/90/09.
  Research Type: Methodology. No publication required.
  
• Informing the development of performance ratings. HTA Ref: 06/90/10.
  Research Type: Methodology. No publication required.
  
• What is the value to society of a QALY? An investigation among the public of England and Wales. HTA Ref: 06/90/04.
  Research Type: Methodology. No publication required.
  
• A study to establish the feasibility of a trial that would investigate the clinical and cost-effectiveness of stopping bisphosphonate treatment after 5 years in post-menopausal women with osteoporosis who have already had a fracture. HTA Ref: 06/31/01.
  Research Type: HTA Technology Assessment Report. No publication required.
  

Thu, 8 May 2008 14:21:52 +0100

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