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Details of HTA journal title

Last updated: 26 August 2008 - Next update due: 2 September 2008

Research type:	Secondary Research (e.g. systematic review)
Title (lead author) etc:	A comparison of the cost-effectiveness of five strategies for the prevention of non-steroidal anti-inflammatory drug-induced gastrointestinal toxicity: a systematic review with economic modelling (Brown) 202 pages, Volume 10, number 38
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Outputs in journals arising from this project
Headline:	Study suggests the most cost-effective strategies for avoiding endoscopic ulcers in patients requiring long-term non-steroidal anti-inflammatory drugs (NSAIDs) are Cox-1 NSAID plus histamine-2 receptor antagonist for low-risk patients and Cox-1 NSAID plus proton pump inhibitors for high-risk patients.
Project ref:	01/40/02
Original project title:	A comparison of the cost-effectiveness of four strategies for the prevention of non-steroidal anti-inflammatory drug (NSAID) induced gastrointestinal toxicity - a systematic review with economic modelling
Chief Investigator:	Professor Deborah Pauline Mary Symmons, Prof Rheumatology and Musculoskeletal Epidemiology, ARC Epidemiology Unit, University of Manchester
Start Date:	June 2002.
Publication date:	October 2006
Cost:	£80,308
MeSH* index primary terms:	ANTI-INLAMMATORY-AGENTS-NON-STEROIDAL Q-adverse-effects; GASTROINTESTINAL-DISEASES Q-chemically-induced (* = Medical Subject Headings)
MeSH* index secondary terms:	HUMAN; RANDOMIZED-CONTROLLED-TRIAL; CLINICAL-TRIAL; QUALITY-OF-LIFE; COST-BENEFIT-ANALYSIS (* = Medical Subject Headings)
NRR* number, if applicable:	N0484112113 (*National Research Register)
Project Protocol:	Project protocol not available
Printed copies of this title despatched:	113 (Figures relate to the previous calendar month)
Downloads/Views of electronic version from website:	40044 (Figures are cumulative.) Last updated 8th July 2008.
URL of this page:	http://www.hta.ac.uk/1300