Direct link to this page: http://www.hta.ac.uk/1302

Details of HTA journal title

Last updated: 15 July 2008 - Next update due: 22 July 2008

Research type:

Primary Research (e.g. trial) 

Title (lead author) etc:

Topical or oral ibuprofen for chronic knee pain in older people. The TOIB study  (Underwood) 176 pages, Volume 12, number 22
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Outputs in journals arising from this project

Headline:

Study on whether GPs should advise their older patients with chronic knee pain to use topical or oral non-steroidal anti-inflammatory drugs (NSAIDs) found that oral NSAIDs appear to produce more minor adverse effects than topical NSAIDs. 

Project ref:

01/09/02 

Original project title:

Are topical or oral Ibuprofen equally effective for the treatment of chronic knee pain in older people (Topical or Oral Ibuprofen TOIB) 

Chief Investigator:

Professor Martin Underwood, Vice-Dean, Health Sciences Research Institute, Warwick Medical School, University of Warwick

Start Date:

July 2002.  

Publication date:

May 2008

Cost:

£725,617 

MeSH* index primary terms:

ARTHRALGIA Q-drug-therapy; IBUPROFEN Q-therapeutic-use; ANALGESICS-NON-NARCOTIC (* = Medical Subject Headings)

MeSH* index secondary terms:

HUMAN; RANDOMIZED-CONTROLLED-TRIAL; CLINICAL-TRIAL; QUESTIONNAIRES; KIDNEY Q-physiology; HEMOGLOBINS Q-analysis; FERRITIN Q-analysis; BLOOD-PRESSURE; LUNG Q-physiology  (* = Medical Subject Headings)

ISRCTN* number:

ISRCTN 79353052 (*International Standard Randomised Controlled Trial Number) 
URL of this project on the Controlled Trials Website:
http://www.controlled-trials.com/ISRCTN79353052 

NRR* number, if applicable:

N0484112114 (*National Research Register) 

Project Protocol:

Project protocol (pdf format, 171 kbytes)

Printed copies of this title despatched:

116 (Figures relate to the previous calendar month)

Downloads/Views of electronic version from website:

1771 (Figures are cumulative.) Last updated 8th July 2008.

URL of this page:

http://www.hta.ac.uk/1302
Tue, 15 Jul 2008 15:23:34 +0100

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